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The U.S. Food and Drug Administration approved Danish drugmaker H. Lundbeck A/S and Japan’s Otsuka Pharmaceutical Co Ltd’s Rexulti, an anti-psychotic drug used to treat schizophrenia. The drug, brexpiprazole, was also approved as an adjunctive therapy for major depressive disorder
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The selective serotonin reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist vilazodone (Viibryd, Forest Laboratories, Inc), currently approved for the treatment of major depressive disorder (MDD) in adults, is also effective in relieving anxiety symptoms in patients with generalized anxiety
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Elevated activation of the kynurenine pathway (KP) may be an objective signal of suicidality in adolescents with major depressive disorder (MDD), new research indicates. In a study of 50 depressed teens with MDD, KP activation was elevated in those with
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Researchers at the George Washington University (GW), led by Michael S. Irwig, M.D., found that men referred for tertiary care for borderline testosterone levels had much higher rates of depression and depressive symptoms than those of the general population. “In
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Women, although possibly not men, who have chronic liver disease with depression experience significant improvement in depressive symptoms when treated with vitamin D therapy to correct the underlying vitamin D deficiency, new research shows. “The gender difference in response to
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We all feel emotion, we all get upset, can feel low, angry and overjoyed, but when do these emotional responses become something of a medical concern? When are these feelings inappropriate, too intense, or lasting too long? When is the
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NeuroRx Inc said initial results of a small study show a combination of several drugs can reduce symptoms of depression and suicidal tendencies in patients with bipolar disorder and maintain that effect over time. The peer-reviewed study of eight patients,
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Researchers at Inserm (Inserm Unit 930 “Imaging and Brain”) attached to François-Rabelais University and Tours Regional University Hospital have combined three clinical, neurophysiological and genetic approaches in order to better understand the brain mechanisms that cause autism. When tested on
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Although schizophrenia patients with the 22q11.2 gene deletion (22q11.2DS) respond to clozapine (multiple brands) at a lower dose than other patients, they experience more serious adverse events, say Canadian researchers in findings that may pave the way for personalized medicine
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Areas of the brain involved in the regulation of emotion develop differently in adolescents with bipolar disorder, new research shows. Investigators at Yale School of Medicine, New Haven, Connecticut, found that adolescents with bipolar disorder showed greater gray matter reduction
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Scientists at Duke Medicine have produced a 3-D map of the human brain stem at an unprecedented level of detail using MRI technology. In a study to be published June 3 in Human Brain Mapping, the researchers unveil an ultra
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Persistent depression may double the risk for stroke in adults aged 50 years and older, and stroke risk remains elevated even when symptoms remit, suggesting a cumulative etiologic mechanisms linking depression and stroke, new research shows. “Multiple prior studies” have
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