Skip to content

Need to talk? Call or text 988 (US)

RecurrentDepression

Classic psychedelic use protective with regard to psychological distress and suicidality

David Mazoor, M.D.Published January 21, 20152 min read

Key points

  • Classic psychedelics, such as LSD, psilocybin mushrooms and mescaline, previously have been shown to occasion lasting improvements in mental health.
  • “Despite advances in mental health treatments, suicide rates generally have not declined in the past 60 years.
  • This study was recently published in the Journal of Psychopharmacology.
  • Approximately 30,000 lives in the United States are claimed by suicide every year, and more than 90 percent of victims have been diagnosed with mental illness, according to the National Alliance on Mental Illness.

Classic psychedelics, such as LSD, psilocybin mushrooms and mescaline, previously have been shown to occasion lasting improvements in mental health. But researchers led by University of Alabama at Birmingham School of Public Health investigators wanted to advance the existing research and determine whether classic psychedelics might be protective with regard to suicidal thoughts and behaviors.

Approximately 30,000 lives in the United States are claimed by suicide every year, and more than 90 percent of victims have been diagnosed with mental illness, according to the National Alliance on Mental Illness.

Using data from more than 190,000 respondents of the National Survey on Drug Use and Health from 2008-2012, the researchers found that those who reported ever having used a classic psychedelic drug in their lifetime had a decreased likelihood of psychological distress in the past month, and decreased suicidal thinking, planning and attempts in the past year.

“Despite advances in mental health treatments, suicide rates generally have not declined in the past 60 years. Novel and potentially more effective interventions need to be explored,” said Peter S. Hendricks, Ph.D., assistant professor in the Department of Health Behavior and lead study author. “This study sets the stage for future research to test the efficacy of classic psychedelics in addressing suicidality as well as pathologies associated with increased suicide risk (e.g., affective disturbance, addiction and impulsive-aggressive personality traits).”

Hendricks says the take-home message from this study is that classic psychedelics may hold great promise in the prevention of suicide and evaluating the therapeutic effectiveness of classic psychedelics should be a priority for future research.

###

This study was recently published in the Journal of Psychopharmacology.

###

Nicole Wyatt
nwyatt@uab.edu
205-934-8938

Revised and edited by

David Mazoor, M.D.

Medically reviewedLast reviewed

The content on this site is for information only and is not a substitute for professional medical advice, diagnosis or treatment. If you are in crisis, call or text 988 (US) or your local emergency number.

If you need help now

Reaching out is a sign of strength.

If you are thinking about suicide or worried about someone, talk to someone today. In an emergency, call your local emergency number.