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Treatment of victims of trauma

Not all traumatic events cause post-traumatic stress disorder (PTSD), and people develop PTSD symptoms after events that do not seem to be overwhelmingly traumatic. In order to direct services appropriately, there is a need to distinguish time-limited post-traumatic symptoms and

6 min read

Post – traumatic stress disorder, resilience and vulnerability

Post-traumatic stress disorder (PTSD), recognised as a diagnostic entity in 1980, was originally associated with combat or war experiences. It has since been recognised that it is prevalent in any population exposed to traumatic events. Although much has been written

15 min read

Neurodevelopmental aspects and developmental precursors of schizophrenia

There is strong evidence that schizophrenia is a neurodevelopmental disorder. Changes in brain structure have been reported in numerous studies of schizophrenia (Keshavan et al, 2005). One focus of epidemiological studies has been the premorbid state and the definition of

9 min read

Genetic aspects of schizophrenia and schizotypy

It is well established that schizophrenia has a sizeable genetic component and that schizotypy may share common genetic vulnerability with schizophrenia. Meehl (1989) postulated the concept of schizotaxia, anunderlying genetic vulnerability to both schizophrenia and schizotypy. Schizotaxia is apparent in

4 min read

Treatment of Recurrent Unipolar Depression

The trial by Hochstrasser et al (2001, this issue) provides a timely reminder of the need for such prolonged treatment of recurrent unipolar depression and reinforces the evidence base and conclusions regarding prolonged treatment of recurrent depression in the BAP

3 min read

Recurrent unipolar depression requires prolonged treatment

Psychiatric disorder is now recognised as one of the greatest causes of human suffering. The burden to society of various diseases has been quantified recently using disability-adjusted life years (DALYs), a measure that expresses years of life lost to premature

6 min read

Diagnosis of depression in general practice

Depression is well recognized as a public health problem that usually runs the risk of becoming chronic, disabling and life threatening if left untreated. Unfortunately depression remains largely under diagnosed in primary care although more than one in ten cases

21 min read

Prevalence of depression among adolescents

OBJECTIVE : To find out the prevalence and pattern of depression among adolescents. METHODS : Adolescents of age group from 13 to 19 belonging to school/college students and school dropouts were assessed using Beck’s Depression Inventory (BDI) by a team

7 min read

Social and cognitive functioning, urbanicity and risk for schizophrenia

Background Previous work suggests that the association between urbanicity and schizophrenia may be greatest in those with pre-existing vulnerability. Aims To test for synergism in risk of schizophrenia between population density and a combined exposure of poor premorbid social and

2 min read

Speed, Ecstasy and Ritalin: The Science of Amphetamines

The 2005/06 British Crime Survey estimated that ecstasy and amphetamines were the third and fourth (after cannabis and cocaine) most widely used illicit drugs among 16- to 59-year-olds (by 1.6% and 1.3% respectively) in England and Wales. More worryingly, among

3 min read

Mortality and electroconvulsive therapy

Munk-Olsen et al (2007) reported that the mortality rate from natural causes was lower for patients undergoing electroconvulsive therapy (ECT) than for other psychiatric in-patients. The lower relative risk was particularly significant for mortality linked to respiratory disease (RR=0.67, 95%

3 min read

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