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Abstract OBJECTIVE: The authors investigated whether quality improvement programs for depression would be effective among substance misusers and whether there would be a differential program-by-comorbidity effect. METHOD: A group-level randomized controlled trial (Partners in Care) compared two quality improvement programs
7 min read
ABSTRACT The effectiveness of screening and organisational strategies to improve the recognition and management of depression in primary care published in a recent issue of Effective Health Care is reviewed. Depression is the second most common cause of disability worldwide.
7 min read
Multiple sclerosis patients who smoke marijuana in search of symptom relief are more likely to suffer cognitive shortfalls and mood disorders, new Canadian research suggests. A slowing down in the ability to process and remember information is one significant side
3 min read
We seem to be in an ongoing analysis of why people lie … First, clients to therapists. And now we bring you a well-written, in-depth article in yesterday’s New York Magazine about why kids lie. The findings from one of
4 min read
A new study suggest elevated levels of anxiety may cause women with ductal carcinoma in situ (DCIS), the most common form of non-invasive breast cancer, to overestimate their risk of recurrence or dying from breast cancer. “Although DCIS typically is
3 min read
The authors are employed by the Medical Research Council at the Social, Genetics, and Developmental Psychiatry Research Centre, part of the Institute of Psychiatry, King’s College London, UK. James Cole (pictured) is an experimental psychology graduate from the University of
13 min read
Background: Atypical antipsychotics are increasingly used in the treatment of a broad spectrum of psychiatric disorders. There is evidence that in addition to treating the positive and negative symptoms of schizophrenia, as well as mania in bipolar disorder, these agents
1 min read
Background Chlorpromazine and haloperidol are benchmark antipsychotic drugs. Both are said to be equally effective when used at equivalent doses, but have different side-effect profiles. Objectives To compare the effects of haloperidol and chlorpromazine for people with schizophrenia and schizophrenia-like
3 min read
Recent reports describe discontinuation-emergent adverse events upon cessation of selective serotonin reuptake inhibitors including dizziness, insomnia, nervousness, nausea, and agitation. We hypothesized that interruption of fluoxetine treatment would be associated with fewer discontinuation-emergent adverse events than interruption of sertraline or
2 min read
Sudden discontinuation of serotonin reuptake inhibitors (SRI) can lead to a number of psychological (e.g., nervousness, anxiety, crying spells, psychomotor agitation, irritability, depersonalization, decreased mood, memory disturbances, confusion, decreased concentration, and/or slowed thinking) and somatic (e.g., nausea, dizziness, headache) symptoms.
9 min read
Synosia Therapeutics has announced the successful completion of its first clinical trial, a proof-of-concept study that evaluated new therapeutic options for SYN-111, a sodium channel blocker. The placebo-controlled, double-blind, three-dose study measured drug effect and pattern of response using quantitative
1 min read
Sam Ozersky’s voice still rings with incredulity when he talks about the American study that changed his thinking about treating patients with mood disorders. The 1996 study compared two groups of 300 people being treated for depression by their family
10 min read
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