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Recent reports describe discontinuation-emergent adverse events upon cessation of selective serotonin reuptake inhibitors including dizziness, insomnia, nervousness, nausea, and agitation. We hypothesized that interruption of fluoxetine treatment would be associated with fewer discontinuation-emergent adverse events than interruption of sertraline or
2 min read
Sudden discontinuation of serotonin reuptake inhibitors (SRI) can lead to a number of psychological (e.g., nervousness, anxiety, crying spells, psychomotor agitation, irritability, depersonalization, decreased mood, memory disturbances, confusion, decreased concentration, and/or slowed thinking) and somatic (e.g., nausea, dizziness, headache) symptoms.
9 min read
Synosia Therapeutics has announced the successful completion of its first clinical trial, a proof-of-concept study that evaluated new therapeutic options for SYN-111, a sodium channel blocker. The placebo-controlled, double-blind, three-dose study measured drug effect and pattern of response using quantitative
1 min read
Sam Ozersky’s voice still rings with incredulity when he talks about the American study that changed his thinking about treating patients with mood disorders. The 1996 study compared two groups of 300 people being treated for depression by their family
10 min read
Findings from what is believed to be the largest comparison of blood samples collected from healthy individuals and people with schizophrenia suggest that infection with the common Toxoplasma gondii parasite, carried by cats and farm animals, may increase the risk
3 min read
Ared-faced toddler pounding her fists on the floor, wailing and screaming, seemingly inconsolable. It’s a perennial occurrence in grocery stores and kitchens across the country. But a temper tantrum may mean more than a child being hungry, tired or not
6 min read
Depression can come into a student’s life without telltale glumness and the blues – it can be relentless fatigue, edgy temper, inability to concentrate and constant friction with roommates. “Depression is the number one issue students bring to our office,”
4 min read
Most children are able to imagine their future selves as astronauts, politicians or even superheroes; however, many older adults find it difficult to recollect past events, let alone generate new ones. A new Harvard University study reveals that the ability
2 min read
Giving birth is not always a joyous occasion. Health experts say childbirth can trigger negative emotions that women are not expecting and are not prepared to handle. While they won’t comment specifically about a Fresno mother accused of drowning her
5 min read
Bright light therapy can ease bipolar depression in some patients, according to a study published in the journal Bipolar Disorders. Researchers from the University of Pittsburgh School of Medicine’s Western Psychiatric Institute and Clinic studied nine women with bipolar disorder
3 min read
Back in 1999, the American Psychological Association published a report calling exercise “an effective but under-used treatment” for mild to moderate depression. The implied call to action was largely ignored. Despite continued research supporting the notion that physical activity can
8 min read
Researchers at Cedars-Sinai Medical Center’s Department of Psychiatry and Behavioral Neurosciences are seeking participants for a clinical trial examining whether two polyunsaturated Omega-3 fatty acids are effective treatments for depression. The two fatty acids being studied – docosahexanoic acid (DHA)
4 min read
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