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Specific culture-related features are discussed in the text for Major Depressive Episode. Epidemiological studies suggest significant cohort effects in risk of depression. For example, individuals born between 1940 and 1950 appear to have an earlier age at onset and a
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Major Depressive Disorder may begin at any age, with an average age at onset in the mid-20s. Epidemiological data suggest that the age at onset is decreasing for those born more recently. The course of Major Depressive Disorder, Recurrent, is
4 min read
The essential feature of Major Depressive Disorder is a clinical course that is characterized by one or more Major Depressive Episodes (see page 349) without a history of Manic, Mixed, or Hypomanic Episodes (Criteria A and C). Episodes of Substance-Induced
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If the full criteria are currently met for a Major Depressive Episode, the following specifiers may be used to describe the current clinical status of the episode and to describe features of the current episode: Mild, Moderate, Severe Without Psychotic
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